Abstract:
Psyllium husk is functional in prevention and cure of physiological ailments like
hypercholesterolemia. Cookies were prepared with addition of 20% psyllium husk along with
control to appraise the efficacy of psyllium husk in normal and hypercholesterolemic subjects.
Cookies were provided to each subject for administering 10 g/day fibre. In normal subjects
research was conducted in years 2009-10 and 2010-11 to get sturdy results trailing the same in
hypercholesterolemics. Statistical analysis revealed that in normal subjects lipid profile affected
non-significantly and significant impact on lipid profile of hypercholesterolemics was noted.
Elevated base line concentration of cholesterol 231.50+_6.46 mg/dL, LDL 158.78+_8.91 mg/dL,
VLDL 35.92+_1.36 mg/dL and LDL/HDL 4.99+_0.25 were significantly reduced to 202.90+_7.26
mg/dL, 134.60+_8.13 mg/dL, 30.40+_1.05 mg/dL and 4.09+_0.17, respectively in 2009-10. Similar
momentous decline was noted in 2010-11. Percent decrease in cholesterol was 12.35 & 11.26%,
LDL 15.22 & 14.10% and VLDL 13.48 & 12.08%, respectively during two years for
hypercholestrolemic subjects. Conclusively, present explorations indicate that psyllium husk diet
is potent as functional component against hypercholesterolemia and is friendly to normal
subjects. |
