Authors: Yuko Horii, Yoshiyuki Fujisaki, Yoshiko Misonou, Hideo Togase, Katsuya Nagai |
Abstract: Certain fermented foods have been shown to have positive effects on health. To determine the effects of a mixed microbial culture of Lactobacillus paracasei, Pichia membranifaciens, and Saccharomyces cerevisiae (LBS culture), we focused on the effect of dermal application of LBS culture on adrenal sympathetic nerve activity (ASNA) and cutaneous arterial sympathetic nerve activity (CASNA),and the effect of intra gastric administration of LBS culture on celiac vagal nerve activity (CVNA) in urethane-anesthetized rats. Results revealed that 1) Dermal application of 100-fold diluted LBS culture significantly reduced both ASNA and CASNA, and 2) intra gastric administration of 10,000-fold diluted LBS culture significantly elevated CVNA. Since the suppression of ASNA leads to decrease in adrenaline and noradrenaline secretions,and since these hormones have been reported to elevate blood glucose and blood pressure, our findings suggest that LBS culture may lower blood glucose and blood pressure. Suppression of CASNA |